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IWANN
2009
Springer
14 years 2 months ago
Identifying Gene Ontology Areas for Automated Enrichment
Biomedical ontologies provide a commonly accepted scheme for the characterization of biological concepts that enable knowledge sharing and integration. Updating and maintaining an ...
Catia Pesquita, Tiago Grego, Francisco M. Couto
IMSCCS
2006
IEEE
14 years 1 months ago
Combining Comparative Genomics with de novo Motif Discovery to Identify Human Transcription Factor DNA-Binding Motifs
Background: As more and more genomes are sequenced, comparative genomics approaches provide a methodology for identifying conserved regulatory elements that may be involved in gen...
Linyong Mao, W. Jim Zheng
SSDBM
2006
IEEE
163views Database» more  SSDBM 2006»
14 years 1 months ago
ACache: Using Caching to Improve the Performance of Multiple Sequence Alignments
Multiple sequence alignment represents a class of powerful bioinformatics tools with many uses in computational biology ranging from discovery of characteristic motifs and conserv...
Xun Tu, Kajal T. Claypool, Cindy X. Chen
CIKM
2005
Springer
14 years 1 months ago
Semantic similarity over the gene ontology: family correlation and selecting disjunctive ancestors
Many bioinformatics applications would benefit from comparing proteins based on their biological role rather than their sequence. In most biological databases, proteins are alrea...
Francisco M. Couto, Mário J. Silva, Pedro C...
PREMI
2005
Springer
14 years 1 months ago
Computational Molecular Biology of Genome Expression and Regulation
Abstract. Technological advances in experimental and computational molecular biology have revolutionized the whole fields of biology and medicine. Large-scale sequencing, expressio...
Michael Q. Zhang