1348 search results - page 230 / 270 » From Informatics to Bioinformatics |
BMCBI
2008
13 years 7 months ago
2008
Background: The most renowned biological ontology, Gene Ontology (GO) is widely used for annotations of genes and gene products of different organisms. However, there are shortcom...
BMCBI
2006
13 years 7 months ago
2006
Background: Detecting remote homologies by direct comparison of protein sequences remains a challenging task. We had previously developed a similarity score between sequences, cal...
BMCBI
2006
13 years 7 months ago
2006
Background: Sequence comparison is one of the most prominent tools in biological research, and is instrumental in studying gene function and evolution. The rapid development of hi...
BMCBI
2006
13 years 7 months ago
2006
Background: Statistical methods for identifying positively selected sites in protein coding regions are one of the most commonly used tools in evolutionary bioinformatics. However...
BMCBI
2006
13 years 7 months ago
2006
Background: Protein-protein interaction (PPI) databases have become a major resource for investigating biological networks and pathways in cells. A number of publicly available re...