RNA genes lack most of the signals used for protein gene identification. A major shortcoming of previous discriminative methods to distinguish functional RNA (fRNA) genes from oth...
Richard F. Meraz, Xiaofeng He, Chris H. Q. Ding, S...
Background: Shared-usage high throughput screening (HTS) facilities are becoming more common in academe as large-scale small molecule and genome-scale RNAi screening strategies ar...
Andrew N. Tolopko, John P. Sullivan, Sean D. Erick...
Background: We observe two trends in bioinformatics: (i) analyses are increasing in complexity, often requiring several applications to be run as a workflow; and (ii) multiple CPU...
Francis Tang, Ching Lian Chua, Liang-Yoong Ho, Yun...
A bioinformatics analysis pipeline is often highly elaborate, due to the inherent complexity of biological systems and the variety and size of laboratory publications would be high...
Marco Roos, Sean Bechhofer, Jun Zhao, Paolo Missie...
There is a diversity of functional genomics data, such as gene expression data from microarray experiments, phenotypic data from gene deletion experiments, protein-protein interac...