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PRIB
2010
Springer
192views Bioinformatics» more  PRIB 2010»
13 years 7 months ago
Structured Output Prediction of Anti-cancer Drug Activity
We present a structured output prediction approach for classifying potential anti-cancer drugs. Our QSAR model takes as input a description of a molecule and predicts the activity...
Hongyu Su, Markus Heinonen, Juho Rousu
WABI
2010
Springer
172views Bioinformatics» more  WABI 2010»
13 years 7 months ago
Fast Mapping and Precise Alignment of AB SOLiD Color Reads to Reference DNA
Abstract. Applied Biosystems’ SOLiD system offers a low-cost alternative to the traditional Sanger method of DNA sequencing. We introduce two main algorithms of mapping SOLiD’...
Miklós Csürös, Szilveszter Juhos,...
WABI
2010
Springer
143views Bioinformatics» more  WABI 2010»
13 years 7 months ago
Swiftly Computing Center Strings
The center string (or closest string) problem is a classical computer science problem with important applications in computational biology. Given k input strings and a distance thr...
Franziska Hufsky, Léon Kuchenbecker, Kathar...
ISBRA
2010
Springer
13 years 6 months ago
Residue Contexts: Non-sequential Protein Structure Alignment Using Structural and Biochemical Features
The study of non-sequential alignments, with different connectivity of the aligned fragments in the proteins being compared can offer a more complete picture of the structural, evo...
Jay W. Kim, Rahul Singh
BIBE
2010
IEEE
142views Bioinformatics» more  BIBE 2010»
13 years 4 months ago
Compressed q-Gram Indexing for Highly Repetitive Biological Sequences
The study of compressed storage schemes for highly repetitive sequence collections has been recently boosted by the availability of cheaper sequencing technologies and the flood of...
Francisco Claude, Antonio Fariña, Miguel A....