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» From Sequence to Biology: The Impact on Bioinformatics
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BIBE
2007
IEEE
128views Bioinformatics» more  BIBE 2007»
14 years 1 months ago
QOMA2: Optimizing the alignment of many sequences
Abstract—We consider the problem of aligning multiple protein sequences with the goal of maximizing the SP (Sum-of-Pairs) score, when the number of sequences is large. The QOMA (...
Xu Zhang, Tamer Kahveci
BMCBI
2006
137views more  BMCBI 2006»
13 years 7 months ago
Sigma: multiple alignment of weakly-conserved non-coding DNA sequence
Background: Existing tools for multiple-sequence alignment focus on aligning protein sequence or protein-coding DNA sequence, and are often based on extensions to Needleman-Wunsch...
Rahul Siddharthan
CF
2009
ACM
14 years 2 months ago
Quantitative analysis of sequence alignment applications on multiprocessor architectures
The exponential growth of databases that contains biological information (such as protein and DNA data) demands great efforts to improve the performance of computational platforms...
Friman Sánchez, Alex Ramírez, Mateo ...
BMCBI
2006
136views more  BMCBI 2006»
13 years 7 months ago
EMD: an ensemble algorithm for discovering regulatory motifs in DNA sequences
Background: Understanding gene regulatory networks has become one of the central research problems in bioinformatics. More than thirty algorithms have been proposed to identify DN...
Jianjun Hu, Yifeng D. Yang, Daisuke Kihara
BIBM
2007
IEEE
132views Bioinformatics» more  BIBM 2007»
14 years 1 months ago
A Divide-and-Conquer Implementation of Three Sequence Alignment and Ancestor Inference
In this paper, we present an algorithm to simultaneously align three biological sequences with affine gap model and infer their common ancestral sequence. Our algorithm can be fu...
Feng Yue, Jijun Tang