165 search results - page 30 / 33 » From Sequence to Biology: The Impact on Bioinformatics |
BMCBI
2010
13 years 7 months ago
2010
Background: Clustering the information content of large high-dimensional gene expression datasets has widespread application in "omics" biology. Unfortunately, the under...
BMCBI
2006
13 years 7 months ago
2006
Background: The number and the arrangement of subunits that form a protein are referred to as quaternary structure. Quaternary structure is an important protein attribute that is ...
BMCBI
2008
13 years 7 months ago
2008
Background: Due to recent progress in genome sequencing, more and more data for phylogenetic reconstruction based on rearrangement distances between genomes become available. Howe...
BMCBI
2006
13 years 7 months ago
2006
Background: DNA copy number alterations are one of the main characteristics of the cancer cell karyotype and can contribute to the complex phenotype of these cells. These alterati...
BMCBI
2005
13 years 7 months ago
2005
Background: Microarray-based measurement of mRNA abundance assumes a linear relationship between the fluorescence intensity and the dye concentration. In reality, however, the cal...