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    BMCBI
    2008
    142views more  BMCBI 2008»
    Strategies for measuring evolutionary conservation of RNA secondary structures
    13 years 8 months ago
    Strategies for measuring evolutionary conservation of RNA secondary structures
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    Background: Evolutionary conservation of RNA secondary structure is a typical feature of many functional non-coding RNAs. Since almost all of the available methods used for predic...
    Andreas R. Gruber, Stephan H. F. Bernhart, Ivo L. ...
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    BMCBI
    2008
    115views more  BMCBI 2008»
    Principal components analysis based methodology to identify differentially expressed genes in time-course microarray data
    13 years 8 months ago
    Principal components analysis based methodology to identify differentially expressed genes in time-course microarray data
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    Background: Time-course microarray experiments are being increasingly used to characterize dynamic biological processes. In these experiments, the goal is to identify genes differ...
    Sudhakar Jonnalagadda, Rajagopalan Srinivasan
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    BMCBI
    2008
    167views more  BMCBI 2008»
    Expression profiles of switch-like genes accurately classify tissue and infectious disease phenotypes in model-based classificat
    13 years 8 months ago
    Expression profiles of switch-like genes accurately classify tissue and infectious disease phenotypes in model-based classificat
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    Background: Large-scale compilation of gene expression microarray datasets across diverse biological phenotypes provided a means of gathering a priori knowledge in the form of ide...
    Michael Gormley, Aydin Tozeren
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    BMCBI
    2008
    107views more  BMCBI 2008»
    Probe-specific mixed-model approach to detect copy number differences using multiplex ligation-dependent probe amplification (ML
    13 years 8 months ago
    Probe-specific mixed-model approach to detect copy number differences using multiplex ligation-dependent probe amplification (ML
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    Background: MLPA method is a potentially useful semi-quantitative method to detect copy number alterations in targeted regions. In this paper, we propose a method for the normaliz...
    Juan R. González, Josep L. Carrasco, Llu&ia...
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    BMCBI
    2008
    88views more  BMCBI 2008»
    Microarray-based gene set analysis: a comparison of current methods
    13 years 8 months ago
    Microarray-based gene set analysis: a comparison of current methods
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    Background: The analysis of gene sets has become a popular topic in recent times, with researchers attempting to improve the interpretability and reproducibility of their microarr...
    Sarah Song, Michael A. Black
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