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BMCBI
2008
83views more  BMCBI 2008»
13 years 9 months ago
Prioritization of gene regulatory interactions from large-scale modules in yeast
Background: The identification of groups of co-regulated genes and their transcription factors, called transcriptional modules, has been a focus of many studies about biological s...
Ho-Joon Lee, Thomas Manke, Ricardo Bringas, Martin...
BMCBI
2006
166views more  BMCBI 2006»
13 years 8 months ago
bioNMF: a versatile tool for non-negative matrix factorization in biology
Background: In the Bioinformatics field, a great deal of interest has been given to Non-negative matrix factorization technique (NMF), due to its capability of providing new insig...
Alberto D. Pascual-Montano, Pedro Carmona-Saez, Mo...
BMCBI
2010
178views more  BMCBI 2010»
13 years 9 months ago
An improved method for scoring protein-protein interactions using semantic similarity within the Gene Ontology
Background: Semantic similarity measures are useful to assess the physiological relevance of protein-protein interactions (PPIs). They quantify similarity between proteins based o...
Shobhit Jain, Gary D. Bader
ISBRA
2009
Springer
14 years 3 months ago
Using Gene Expression Modeling to Determine Biological Relevance of Putative Regulatory Networks
Identifying gene regulatory networks from high-throughput gene expression data is one of the most important goals of bioinformatics, but it remains difficult to define what makes a...
Peter Larsen, Yang Dai
BMCBI
2006
163views more  BMCBI 2006»
13 years 8 months ago
Ensemble attribute profile clustering: discovering and characterizing groups of genes with similar patterns of biological featur
Background: Ensemble attribute profile clustering is a novel, text-based strategy for analyzing a userdefined list of genes and/or proteins. The strategy exploits annotation data ...
J. R. Semeiks, A. Rizki, Mina J. Bissell, I. Saira...