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BMCBI
2010
137views more  BMCBI 2010»
13 years 9 months ago
Biana: a software framework for compiling biological interactions and analyzing networks
Background: The analysis and usage of biological data is hindered by the spread of information across multiple repositories and the difficulties posed by different nomenclature sy...
Javier Garcia-Garcia, Emre Guney, Ramon Aragues, J...
BMCBI
2008
160views more  BMCBI 2008»
13 years 9 months ago
Cross-species and cross-platform gene expression studies with the Bioconductor-compliant R package 'annotationTools'
Background: The variety of DNA microarray formats and datasets presently available offers an unprecedented opportunity to perform insightful comparisons of heterogeneous data. Cro...
Alexandre Kuhn, Ruth Luthi-Carter, Mauro Delorenzi
GECCO
2008
Springer
179views Optimization» more  GECCO 2008»
13 years 10 months ago
Evolution of discrete gene regulatory models
Gene regulatory networks (GRNs) are complex control systems that govern the interaction of genes, which ultimately control cellular processes at the protein level. GRNs can be ted...
Afshin Esmaeili, Christian Jacob
AUTOMATICA
2006
88views more  AUTOMATICA 2006»
13 years 8 months ago
Exact computation of amplification for a class of nonlinear systems arising from cellular signaling pathways
A commonly employed measure of the signal amplification properties of an input/output system is its induced L2 norm, sometimes also known as H gain. In general, however, it is ext...
Eduardo D. Sontag, Madalena Chaves
BMCBI
2008
142views more  BMCBI 2008»
13 years 9 months ago
Microarray data mining: A novel optimization-based approach to uncover biologically coherent structures
Background: DNA microarray technology allows for the measurement of genome-wide expression patterns. Within the resultant mass of data lies the problem of analyzing and presenting...
Meng Piao Tan, Erin N. Smith, James R. Broach, Chr...