Sciweavers

549 search results - page 39 / 110
» From genes to functional classes in the study of biological ...
Sort
View
BMCBI
2006
82views more  BMCBI 2006»
13 years 8 months ago
A method for computing the overall statistical significance of a treatment effect among a group of genes
Background: In studies that use DNA arrays to assess changes in gene expression, our goal is to evaluate the statistical significance of treatments on sets of genes. Genes can be ...
Robert R. Delongchamp, Taewon Lee, Cruz Velasco
EDBT
2004
ACM
230views Database» more  EDBT 2004»
14 years 8 months ago
Flexible Integration of Molecular-Biological Annotation Data: The GenMapper Approach
Molecular-biological annotation data is continuously being collected, curated and made accessible in numerous public data sources. Integration of this data is a major challenge in ...
Hong Hai Do, Erhard Rahm
BIOCOMP
2006
13 years 10 months ago
The Generalized Topological Overlap Matrix for Detecting Modules in Gene Networks
Systems biologic studies of gene and protein interaction networks have found that these networks are comprised of `modules' (groups of tightly interconnected nodes). Module i...
Andy M. Yip, Steve Horvath
BMCBI
2006
122views more  BMCBI 2006»
13 years 8 months ago
Computational reconstruction of transcriptional regulatory modules of the yeast cell cycle
Background: A transcriptional regulatory module (TRM) is a set of genes that is regulated by a common set of transcription factors (TFs). By organizing the genome into TRMs, a liv...
Wei-Sheng Wu, Wen-Hsiung Li, Bor-Sen Chen
GCB
2009
Springer
154views Biometrics» more  GCB 2009»
14 years 18 days ago
Comparative Identification of Differential Interactions from Trajectories of Dynamic Biological Networks
Abstract: It is often challenging to reconstruct accurately a complete dynamic biological network due to the scarcity of data collected in cost-effective experiments. This paper ad...
Zhengyu Ouyang, Mingzhou Song