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BMCBI
2011
13 years 22 days ago
Improving pan-genome annotation using whole genome multiple alignment
Background: Rapid annotation and comparisons of genomes from multiple isolates (pan-genomes) is becoming commonplace due to advances in sequencing technology. Genome annotations c...
Samuel V. Angiuoli, Julie C. Dunning Hotopp, Steve...
IDA
2007
Springer
14 years 3 months ago
Learning to Align: A Statistical Approach
We present a new machine learning approach to the inverse parametric sequence alignment problem: given as training examples a set of correct pairwise global alignments, find the p...
Elisa Ricci, Tijl De Bie, Nello Cristianini
CSB
2005
IEEE
130views Bioinformatics» more  CSB 2005»
14 years 2 months ago
TreeRefiner: A Tool for Refining a Multiple Alignment on a Phylogenetic Tree
We present TreeRefiner, a tool for refining multiple alignments of biological sequences. Given a multiple alignment, a phylogenetic tree, and scoring parameters as input, TreeRefi...
Aswath Manohar, Serafim Batzoglou
NAR
2007
121views more  NAR 2007»
13 years 8 months ago
WormBase: new content and better access
WormBase (http://wormbase.org), a model organism database for Caenorhabditis elegans and other related nematodes, continues to evolve and expand. Over the past year WormBase has a...
Tamberlyn Bieri, Darin Blasiar, Philip Ozersky, Ig...
LCTRTS
2000
Springer
14 years 21 days ago
Automatic Validation of Code-Improving Transformations
This paper presents a general approach to automatically validate code-improving transformations on low-level program representations. The approach ensures the correctness of compi...
Robert van Engelen, David B. Whalley, Xin Yuan