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BMCBI
2008
90views more  BMCBI 2008»
13 years 7 months ago
Function2Gene: A gene selection tool to increase the power of genetic association studies by utilizing public databases and expe
Background: Many common disorders have multiple genetic components which convey increased susceptibility. SNPs have been used to identify genetic components which are associated w...
Don L. Armstrong, Chaim O. Jacob, Raphael Zidovetz...
SCFBM
2008
87views more  SCFBM 2008»
13 years 7 months ago
Analysis by siRNA_profile program displays novel thermodynamic characteristics of highly functional siRNA molecules
Objective: Here we report the improved results of a new siRNA design program and analysis tool called siRNA_profile that reveals an additional criterion for bioinformatic search o...
Pirkko Muhonen, Ranga N. Parthasarathy, Anthony J....
GECCO
2007
Springer
184views Optimization» more  GECCO 2007»
13 years 11 months ago
Evolving kernels for support vector machine classification
While support vector machines (SVMs) have shown great promise in supervised classification problems, researchers have had to rely on expert domain knowledge when choosing the SVM&...
Keith Sullivan, Sean Luke
BIOCOMP
2009
13 years 8 months ago
Improving Remote Homology Detection Using Sequence Properties and Position Specific Scoring Matrices
Current biological sequence comparison tools frequently fail to recognize matches between homologs when sequence similarity is below the twilight zone of less than 25% sequence id...
Gina Cooper, Michael L. Raymer
TEC
2008
139views more  TEC 2008»
13 years 7 months ago
Genetic Programming Approaches for Solving Elliptic Partial Differential Equations
In this paper, we propose a technique based on genetic programming (GP) for meshfree solution of elliptic partial differential equations. We employ the least-squares collocation pr...
Andras Sobester, Prasanth B. Nair, Andy J. Keane