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ISMB
2007
13 years 9 months ago
Computational prediction of host-pathogen protein-protein interactions
Our major effort in this reporting period comprised functional genomic studies of key genes for carbon metabolite and nodulation/nitrogen fixation in Sinorhizobium meliloti, compar...
Matthew D. Dyer, T. M. Murali, Bruno W. S. Sobral
BMCBI
2005
155views more  BMCBI 2005»
13 years 7 months ago
Mining protein function from text using term-based support vector machines
Background: Text mining has spurred huge interest in the domain of biology. The goal of the BioCreAtIvE exercise was to evaluate the performance of current text mining systems. We...
Simon B. Rice, Goran Nenadic, Benjamin J. Stapley
BMCBI
2010
139views more  BMCBI 2010»
13 years 7 months ago
RNAstructure: software for RNA secondary structure prediction and analysis
Background: To understand an RNA sequence's mechanism of action, the structure must be known. Furthermore, target RNA structure is an important consideration in the design of...
Jessica S. Reuter, David H. Mathews
BMCBI
2008
142views more  BMCBI 2008»
13 years 7 months ago
Strategies for measuring evolutionary conservation of RNA secondary structures
Background: Evolutionary conservation of RNA secondary structure is a typical feature of many functional non-coding RNAs. Since almost all of the available methods used for predic...
Andreas R. Gruber, Stephan H. F. Bernhart, Ivo L. ...
CSB
2003
IEEE
110views Bioinformatics» more  CSB 2003»
14 years 22 days ago
Statistical Inference for Well-ordered Structures in Nucleotide Sequences
Distinct, local structures are frequently correlated with functional RNA elements involved in posttranscriptional regulation of gene expression. Discovery of microRNAs (miRNAs) su...
Shu-Yun Le, Jih-H. Chen, Jacob V. Maizel