In this paper, we propose a general cross-layer optimization framework in which we explicitly consider both the heterogeneous and dynamically changing characteristics of delay-sens...
Starting from some simple observations on a popular selection method in Evolutionary Algorithms (EAs)--tournament selection--we highlight a previously-unknown source of inefficien...
Background: Detecting remote homologies by direct comparison of protein sequences remains a challenging task. We had previously developed a similarity score between sequences, cal...
Background: Systems biologists work with many kinds of data, from many different sources, using a variety of software tools. Each of these tools typically excels at one type of an...
Paul T. Shannon, David J. Reiss, Richard Bonneau, ...
Background: In our previous studies, we found that the sites in prokaryotic genomes which are most susceptible to duplex destabilization under the negative superhelical stresses t...