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» Functional annotation of regulatory pathways
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ICASSP
2007
IEEE
14 years 1 months ago
Evolutionary Sequence Modeling for Discovery of Peptide Hormones
There are currently a large number of ‘‘orphan’’ G-protein-coupled receptors (GPCRs) whose endogenous ligands (peptide hormones) are unknown. Identification of these pepti...
M. Kemal Sönmez, Lawrence Toll, Nina Zaveri
CSB
2005
IEEE
137views Bioinformatics» more  CSB 2005»
14 years 28 days ago
Improving Operon Prediction in E. coli
In bacterium, genes working in the same pathway or interacting with each other are often organized into operons. Currently, the prediction accuracy for operon/boundary gene pairs ...
PhuongAn Dam, Victor Olman, Ying Xu
BMCBI
2008
167views more  BMCBI 2008»
13 years 7 months ago
Expression profiles of switch-like genes accurately classify tissue and infectious disease phenotypes in model-based classificat
Background: Large-scale compilation of gene expression microarray datasets across diverse biological phenotypes provided a means of gathering a priori knowledge in the form of ide...
Michael Gormley, Aydin Tozeren
BMCBI
2006
155views more  BMCBI 2006»
13 years 7 months ago
AffyMiner: mining differentially expressed genes and biological knowledge in GeneChip microarray data
Background: DNA microarrays are a powerful tool for monitoring the expression of tens of thousands of genes simultaneously. With the advance of microarray technology, the challeng...
Guoqing Lu, The V. Nguyen, Yuannan Xia, Michael Fr...
BMCBI
2010
196views more  BMCBI 2010»
13 years 4 months ago
Content-based microarray search using differential expression profiles
Background: With the expansion of public repositories such as the Gene Expression Omnibus (GEO), we are rapidly cataloging cellular transcriptional responses to diverse experiment...
Jesse M. Engreitz, Alexander A. Morgan, Joel Dudle...