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» Functional annotation of regulatory pathways
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BMCBI
2005
114views more  BMCBI 2005»
13 years 7 months ago
AutoFACT: An Automatic Functional Annotation and Classification Tool
Background: Assignment of function to new molecular sequence data is an essential step in genomics projects. The usual process involves similarity searches of a given sequence aga...
Liisa B. Koski, Michael W. Gray, B. Franz Lang, Ge...
WABI
2009
Springer
124views Bioinformatics» more  WABI 2009»
14 years 1 months ago
Mimosa: Mixture Model of Co-expression to Detect Modulators of Regulatory Interaction
Background: Functionally related genes tend to be correlated in their expression patterns across multiple conditions and/or tissue-types. Thus co-expression networks are often use...
Matthew Hansen, Logan Everett, Larry Singh, Sridha...
BMCBI
2006
181views more  BMCBI 2006»
13 years 7 months ago
Array2BIO: from microarray expression data to functional annotation of co-regulated genes
Background: There are several isolated tools for partial analysis of microarray expression data. To provide an integrative, easy-to-use and automated toolkit for the analysis of A...
Gabriela G. Loots, Patrick S. G. Chain, Shalini Ma...
NAR
2006
177views more  NAR 2006»
13 years 7 months ago
PUMA2 - grid-based high-throughput analysis of genomes and metabolic pathways
The PUMA2 system (available at http://compbio.mcs. 10 anl.gov/puma2) is an interactive, integrated bioinformatics environment for high-throughput genetic sequence analysis and met...
Natalia Maltsev, Elizabeth M. Glass, Dinanath Sula...
BMCBI
2008
142views more  BMCBI 2008»
13 years 7 months ago
Strategies for measuring evolutionary conservation of RNA secondary structures
Background: Evolutionary conservation of RNA secondary structure is a typical feature of many functional non-coding RNAs. Since almost all of the available methods used for predic...
Andreas R. Gruber, Stephan H. F. Bernhart, Ivo L. ...