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RECOMB
2003
Springer
14 years 9 months ago
An integrated probabilistic model for functional prediction of proteins
We develop an integrated probabilistic model to combine protein physical interactions, genetic interactions, highly correlated gene expression network, protein complex data, and d...
Minghua Deng, Ting Chen, Fengzhu Sun
BIBM
2010
IEEE
157views Bioinformatics» more  BIBM 2010»
13 years 6 months ago
Decomposing PPI networks for complex discovery
Abstract--Protein complexes are important for understanding principles of cellular organization and functions. With the availability of large amounts of high-throughput proteinprot...
Guimei Liu, Chern Han Yong, Limsoon Wong, Hon Nian...
BMCBI
2010
160views more  BMCBI 2010»
13 years 8 months ago
Identification of functional hubs and modules by converting interactome networks into hierarchical ordering of proteins
Background: Protein-protein interactions play a key role in biological processes of proteins within a cell. Recent high-throughput techniques have generated protein-protein intera...
Young-Rae Cho, Aidong Zhang
BMCBI
2010
156views more  BMCBI 2010»
13 years 8 months ago
Protein complex prediction via verifying and reconstructing the topology of domain-domain interactions
Background: High-throughput methods for detecting protein-protein interactions enable us to obtain large interaction networks, and also allow us to computationally identify the as...
Yosuke Ozawa, Rintaro Saito, Shigeo Fujimori, Hisa...
SAC
2006
ACM
14 years 2 months ago
Mining and analyzing the topological structure of protein-protein interaction networks
We report a comprehensive evaluation of the topological structure of protein-protein interaction (PPI) networks by mining and analyzing graphs constructed from the publicly availa...
Daniel Duanqing Wu, Xiaohua Hu