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    BMCBI
    2005
    162views more  BMCBI 2005»
    Accelerated probabilistic inference of RNA structure evolution
    13 years 8 months ago
    Accelerated probabilistic inference of RNA structure evolution
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    Background: Pairwise stochastic context-free grammars (Pair SCFGs) are powerful tools for evolutionary analysis of RNA, including simultaneous RNA sequence alignment and secondary...
    Ian Holmes
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    BMCBI
    2005
    151views more  BMCBI 2005»
    stam - a Bioconductor compliant R package for structured analysis of microarray data
    13 years 8 months ago
    stam - a Bioconductor compliant R package for structured analysis of microarray data
    Download  www.biomedcentral.com
    Background: Genome wide microarray studies have the potential to unveil novel disease entities. Clinically homogeneous groups of patients can have diverse gene expression profiles...
    Claudio Lottaz, Rainer Spang
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    BMCBI
    2005
    145views more  BMCBI 2005»
    CAGER: classification analysis of gene expression regulation using multiple information sources
    13 years 8 months ago
    CAGER: classification analysis of gene expression regulation using multiple information sources
    Download  www.biomedcentral.com
    Background: Many classification approaches have been applied to analyzing transcriptional regulation of gene expressions. These methods build models that can explain a gene's...
    Jianhua Ruan, Weixiong Zhang
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    BMCBI
    2005
    105views more  BMCBI 2005»
    SNPHunter: a bioinformatic software for single nucleotide polymorphism data acquisition and management
    13 years 8 months ago
    SNPHunter: a bioinformatic software for single nucleotide polymorphism data acquisition and management
    Download  www.biomedcentral.com
    Background: Single nucleotide polymorphisms (SNPs) provide an important tool in pinpointing susceptibility genes for complex diseases and in unveiling human molecular evolution. S...
    Lin Wang, Simin Liu, Tianhua Niu, Xin Xu
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    BMCBI
    2005
    152views more  BMCBI 2005»
    Improved profile HMM performance by assessment of critical algorithmic features in SAM and HMMER
    13 years 8 months ago
    Improved profile HMM performance by assessment of critical algorithmic features in SAM and HMMER
    Download  www.biomedcentral.com
    Background: Profile hidden Markov model (HMM) techniques are among the most powerful methods for protein homology detection. Yet, the critical features for successful modelling ar...
    Markus Wistrand, Erik L. L. Sonnhammer
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