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BIOINFORMATICS
2006
101views more  BIOINFORMATICS 2006»
13 years 7 months ago
A lock-and-key model for protein-protein interactions
Motivation: Protein-protein interaction networks are one of the major post-genomic data sources available to molecular biologists. They provide a comprehensive view of the global ...
Julie L. Morrison, Rainer Breitling, Desmond J. Hi...
JCB
2006
129views more  JCB 2006»
13 years 7 months ago
GenRate: A Generative Model that Reveals Novel Transcripts in Genome-Tiling Microarray Data
Genome-wide microarray designs containing millions to hundreds of millions of probes are available for a variety of mammals, including mouse and human. These genome tiling arrays ...
Brendan J. Frey, Quaid Morris, Timothy R. Hughes
BMCBI
2010
83views more  BMCBI 2010»
13 years 7 months ago
Trees on networks: resolving statistical patterns of phylogenetic similarities among interacting proteins
Background: Phylogenies capture the evolutionary ancestry linking extant species. Correlations and similarities among a set of species are mediated by and need to be understood in...
William P. Kelly, Michael P. H. Stumpf
IPM
2008
141views more  IPM 2008»
13 years 7 months ago
Towards a unified approach to document similarity search using manifold-ranking of blocks
Document similarity search (i.e. query by example) aims to retrieve a ranked list of documents similar to a query document in a text corpus or on the Web. Most existing approaches...
Xiaojun Wan, Jianwu Yang, Jianguo Xiao
NAR
2008
175views more  NAR 2008»
13 years 7 months ago
Onto-CC: a web server for identifying Gene Ontology conceptual clusters
The Gene Ontology (GO) vocabulary has been extensively explored to analyze the functions of coexpressed genes. However, despite its extended use in Biology and Medical Sciences, t...
Rocío Romero-Záliz, Coral del Val, J...