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BMCBI
2010
135views more  BMCBI 2010»
13 years 7 months ago
HDAPD: a web tool for searching the disease-associated protein structures
Background: The protein structures of the disease-associated proteins are important for proceeding with the structure-based drug design to against a particular disease. Up until n...
Yi-Ruen Lin, Hsin-Yuan Wei, Tsung-Lin Tsai, Thy-Ho...
BMCBI
2010
146views more  BMCBI 2010»
13 years 7 months ago
Revealing and avoiding bias in semantic similarity scores for protein pairs
Background: Semantic similarity scores for protein pairs are widely applied in functional genomic researches for finding functional clusters of proteins, predicting protein functi...
Jing Wang 0004, Xianxiao Zhou, Jing Zhu, Chenggui ...
BMCBI
2010
130views more  BMCBI 2010»
13 years 7 months ago
A statistical approach to finding overlooked genetic associations
Background: Complexity and noise in expression quantitative trait loci (eQTL) studies make it difficult to distinguish potential regulatory relationships among the many interactio...
Andrew K. Rider, Geoffrey Siwo, Nitesh V. Chawla, ...
BMCBI
2005
189views more  BMCBI 2005»
13 years 7 months ago
A sentence sliding window approach to extract protein annotations from biomedical articles
Background: Within the emerging field of text mining and statistical natural language processing (NLP) applied to biomedical articles, a broad variety of techniques have been deve...
Martin Krallinger, Maria Padron, Alfonso Valencia
BMCBI
2004
120views more  BMCBI 2004»
13 years 7 months ago
Optimal cDNA microarray design using expressed sequence tags for organisms with limited genomic information
Background: Expression microarrays are increasingly used to characterize environmental responses and hostparasite interactions for many different organisms. Probe selection for cD...
Yian A. Chen, David J. Mckillen, Shuyuan Wu, Matth...