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» GREAT: Gene Regulation EvAluation Tool
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IWANN
2009
Springer
14 years 5 months ago
GREAT: Gene Regulation EvAluation Tool
Our understanding of biological systems is highly dependent on the study of the mechanisms that regulate genetic expression. In this paper we present a tool to evaluate scientific ...
Catia Machado, Hugo P. Bastos, Francisco M. Couto
BMCBI
2006
127views more  BMCBI 2006»
13 years 11 months ago
Using local gene expression similarities to discover regulatory binding site modules
Background: We present an approach designed to identify gene regulation patterns using sequence and expression data collected for Saccharomyces cerevisae. Our main goal is to rela...
Bartek Wilczynski, Torgeir R. Hvidsten, Andriy Kry...
BMCBI
2010
133views more  BMCBI 2010»
13 years 11 months ago
New components of the Dictyostelium PKA pathway revealed by Bayesian analysis of expression data
Background: Identifying candidate genes in genetic networks is important for understanding regulation and biological function. Large gene expression datasets contain relevant info...
Anup Parikh, Eryong Huang, Christopher Dinh, Blaz ...
BMCBI
2010
110views more  BMCBI 2010»
13 years 11 months ago
GenHtr: a tool for comparative assessment of genetic heterogeneity in microbial genomes generated by massive short-read sequenci
Background: Microevolution is the study of short-term changes of alleles within a population and their effects on the phenotype of organisms. The result of the below-species-level...
GongXin Yu
BMCBI
2008
98views more  BMCBI 2008»
13 years 11 months ago
MTAP: The Motif Tool Assessment Platform
Background: In recent years, substantial effort has been applied to de novo regulatory motif discovery. At this time, more than 150 software tools exist to detect regulatory bindi...
Daniel Quest, Kathryn Dempsey, Mohammad Shafiullah...