Massive publicly available gene expression data consisting of different experimental conditions and microarray platforms introduce new challenges in data mining when integrating m...
Background: The variety of DNA microarray formats and datasets presently available offers an unprecedented opportunity to perform insightful comparisons of heterogeneous data. Cro...
Background: The completion of the sequencing of human, mouse and rat genomes and knowledge of cross-species gene homologies enables studies of differential gene expression in anim...
Hong Fang, Weida Tong, Roger Perkins, Leming M. Sh...
Background: The identification of biologically interesting genes in a temporal expression profiling dataset is challenging and complicated by high levels of experimental noise. Mo...
Selecting the most relevant factors from genetic profiles that can optimally characterize cellular states is of crucial importance in identifying complex disease genes and biomark...