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» Gene Classification using Expression Profiles: A Feasibility...
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BMCBI
2010
135views more  BMCBI 2010»
13 years 7 months ago
Simple and flexible classification of gene expression microarrays via Swirls and Ripples
Background: A simple classification rule with few genes and parameters is desirable when applying a classification rule to new data. One popular simple classification rule, diagon...
Stuart G. Baker
ISMB
2000
13 years 9 months ago
Analysis of Gene Expression Microarrays for Phenotype Classification
Several microarray technologies that monitor the level of expression of a large number of genes have recently emerged. Given DNA-microarray data for a set of cells characterized b...
Andrea Califano, Gustavo Stolovitzky, Yuhai Tu
BMCBI
2008
145views more  BMCBI 2008»
13 years 7 months ago
Mapping gene expression quantitative trait loci by singular value decomposition and independent component analysis
Background: The combination of gene expression profiling with linkage analysis has become a powerful paradigm for mapping gene expression quantitative trait loci (eQTL). To date, ...
Shameek Biswas, John D. Storey, Joshua M. Akey
BMCBI
2004
115views more  BMCBI 2004»
13 years 7 months ago
Quantifying the relationship between co-expression, co-regulation and gene function
Background: It is thought that genes with similar patterns of mRNA expression and genes with similar functions are likely to be regulated via the same mechanisms. It has been diff...
Dominic J. Allocco, Isaac S. Kohane, Atul J. Butte
BMCBI
2008
135views more  BMCBI 2008»
13 years 7 months ago
Identification of a small optimal subset of CpG sites as bio-markers from high-throughput DNA methylation profiles
Background: DNA methylation patterns have been shown to significantly correlate with different tissue types and disease states. High-throughput methylation arrays enable large-sca...
Hailong Meng, Edward Lenn Murrelle, Guoya Li