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» Gene Expression Clustering with Functional Mixture Models
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BMCBI
2005
113views more  BMCBI 2005»
13 years 10 months ago
Systematic survey reveals general applicability of "guilt-by-association" within gene coexpression networks
Background: Biological processes are carried out by coordinated modules of interacting molecules. As clustering methods demonstrate that genes with similar expression display incr...
Cecily J. Wolfe, Isaac S. Kohane, Atul J. Butte
BMCBI
2005
169views more  BMCBI 2005»
13 years 10 months ago
An adaptive method for cDNA microarray normalization
Background: Normalization is a critical step in analysis of gene expression profiles. For duallabeled arrays, global normalization assumes that the majority of the genes on the ar...
Yingdong Zhao, Ming-Chung Li, Richard Simon
CEC
2007
IEEE
14 years 2 months ago
Evolving hypernetwork classifiers for microRNA expression profile analysis
Abstract-- High-throughput microarrays inform us on different outlooks of the molecular mechanisms underlying the function of cells and organisms. While computational analysis for ...
Sun Kim, Soo-Jin Kim, Byoung-Tak Zhang
ICDM
2006
IEEE
145views Data Mining» more  ICDM 2006»
14 years 4 months ago
Stability Region Based Expectation Maximization for Model-based Clustering
In spite of the initialization problem, the ExpectationMaximization (EM) algorithm is widely used for estimating the parameters in several data mining related tasks. Most popular ...
Chandan K. Reddy, Hsiao-Dong Chiang, Bala Rajaratn...
BMCBI
2006
151views more  BMCBI 2006»
13 years 10 months ago
Modeling Sage data with a truncated gamma-Poisson model
Background: Serial Analysis of Gene Expressions (SAGE) produces gene expression measurements on a discrete scale, due to the finite number of molecules in the sample. This means t...
Helene H. Thygesen, Aeilko H. Zwinderman