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» Gene Expression Clustering with Functional Mixture Models
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BMCBI
2005
178views more  BMCBI 2005»
13 years 10 months ago
A quantization method based on threshold optimization for microarray short time series
Background: Reconstructing regulatory networks from gene expression profiles is a challenging problem of functional genomics. In microarray studies the number of samples is often ...
Barbara Di Camillo, Fatima Sanchez-Cabo, Gianna To...
BMCBI
2006
116views more  BMCBI 2006»
13 years 10 months ago
Cluster analysis for DNA methylation profiles having a detection threshold
Background: DNA methylation, a molecular feature used to investigate tumor heterogeneity, can be measured on many genomic regions using the MethyLight technology. Due to the combi...
Paul Marjoram, Jing Chang, Peter W. Laird, Kimberl...
BMCBI
2008
115views more  BMCBI 2008»
13 years 10 months ago
Genome-scale cluster analysis of replicated microarrays using shrinkage correlation coefficient
Background: Currently, clustering with some form of correlation coefficient as the gene similarity metric has become a popular method for profiling genomic data. The Pearson corre...
Jianchao Yao, Chunqi Chang, Mari L. Salmi, Yeung S...
ICML
2004
IEEE
14 years 11 months ago
Boosting margin based distance functions for clustering
The performance of graph based clustering methods critically depends on the quality of the distance function, used to compute similarities between pairs of neighboring nodes. In t...
Tomer Hertz, Aharon Bar-Hillel, Daphna Weinshall
BMCBI
2008
140views more  BMCBI 2008»
13 years 10 months ago
GORouter: an RDF model for providing semantic query and inference services for Gene Ontology and its associations
Background: The most renowned biological ontology, Gene Ontology (GO) is widely used for annotations of genes and gene products of different organisms. However, there are shortcom...
Qingwei Xu, Yixiang Shi, Qiang Lu, Guo-qing Zhang,...