Background: Despite their involvement in the regulation of gene expression and their importance as genomic markers for promoter prediction, no objective standard exists for defini...
Michael Hackenberg, Christopher Previti, Pedro Lui...
Mechanistic models for transcriptional regulation are derived using the methods of equilibrium statistical mechanics, to model equilibrating processes that occur at a fast time sc...
Background: Biologically active sequence motifs often have positional preferences with respect to a genomic landmark. For example, many known transcription factor binding sites (T...
Nak-Kyeong Kim, Kannan Tharakaraman, Leonardo Mari...
This paper presents GMLE 1 , a generic and distributed framework for maximum likelihood evaluation. GMLE is currently being applied to astroinformatics for determining the shape o...
Travis J. Desell, Nathan Cole, Malik Magdon-Ismail...
Graph structure can model the relationships among a set of objects. Mining quasi-clique patterns from large dense graph data makes sense with respect to both statistic and applica...