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BMCBI
2010
190views more  BMCBI 2010»
13 years 7 months ago
APIS: accurate prediction of hot spots in protein interfaces by combining protrusion index with solvent accessibility
Background: It is well known that most of the binding free energy of protein interaction is contributed by a few key hot spot residues. These residues are crucial for understandin...
Jun-Feng Xia, Xing-Ming Zhao, Jiangning Song, De-S...
BMCBI
2005
117views more  BMCBI 2005»
13 years 7 months ago
An SVM-based system for predicting protein subnuclear localizations
Background: The large gap between the number of protein sequences in databases and the number of functionally characterized proteins calls for the development of a fast computatio...
Zhengdeng Lei, Yang Dai
SCFBM
2008
151views more  SCFBM 2008»
13 years 7 months ago
Wndchrm - an open source utility for biological image analysis
Background: Biological imaging is an emerging field, covering a wide range of applications in biological and clinical research. However, while machinery for automated experimentin...
Lior Shamir, Nikita Orlov, D. Mark Eckley, Tomasz ...
KDD
2006
ACM
170views Data Mining» more  KDD 2006»
14 years 8 months ago
Computer aided detection via asymmetric cascade of sparse hyperplane classifiers
This paper describes a novel classification method for computer aided detection (CAD) that identifies structures of interest from medical images. CAD problems are challenging larg...
Jinbo Bi, Senthil Periaswamy, Kazunori Okada, Tosh...
BMCBI
2008
114views more  BMCBI 2008»
13 years 7 months ago
Identifying a few foot-and-mouth disease virus signature nucleotide strings for computational genotyping
Background: Serotypes of the Foot-and-Mouth disease viruses (FMDVs) were generally determined by biological experiments. The computational genotyping is not well studied even with...
Guohui Lin, Zhipeng Cai, Junfeng Wu, Xiu-Feng Wan,...