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» Gene functional classification from heterogeneous data
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133
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BMCBI
2010
87views more  BMCBI 2010»
15 years 3 months ago
Epigenetic domains found in mouse embryonic stem cells via a hidden Markov model
Background: Epigenetics is an important layer of transcriptional control necessary for cell-type specific gene regulation. Recent studies have shown significant epigenetic pattern...
Jessica L. Larson, Guo-Cheng Yuan
137
Voted
KDD
1998
ACM
112views Data Mining» more  KDD 1998»
15 years 8 months ago
Evaluating Usefulness for Dynamic Classification
This paper develops the concept of usefulness in the context of supervised learning. We argue that usefulness can be used to improve the performance of classification rules (as me...
Gholamreza Nakhaeizadeh, Charles Taylor, Carsten L...
140
Voted
BMCBI
2004
135views more  BMCBI 2004»
15 years 3 months ago
Information assessment on predicting protein-protein interactions
Background: Identifying protein-protein interactions is fundamental for understanding the molecular machinery of the cell. Proteome-wide studies of protein-protein interactions ar...
Nan Lin, Baolin Wu, Ronald Jansen, Mark Gerstein, ...
157
Voted
BMCBI
2005
251views more  BMCBI 2005»
15 years 3 months ago
Contextual weighting for Support Vector Machines in literature mining: an application to gene versus protein name disambiguation
Background: The ability to distinguish between genes and proteins is essential for understanding biological text. Support Vector Machines (SVMs) have been proven to be very effici...
Tapio Pahikkala, Filip Ginter, Jorma Boberg, Jouni...
135
Voted
BMCBI
2006
100views more  BMCBI 2006»
15 years 3 months ago
Using the nucleotide substitution rate matrix to detect horizontal gene transfer
Background: Horizontal gene transfer (HGT) has allowed bacteria to evolve many new capabilities. Because transferred genes perform many medically important functions, such as conf...
Micah Hamady, M. D. Betterton, Rob Knight