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» Gene functional classification from heterogeneous data
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BMCBI
2008
157views more  BMCBI 2008»
13 years 10 months ago
Dimension reduction with redundant gene elimination for tumor classification
Background: Analysis of gene expression data for tumor classification is an important application of bioinformatics methods. But it is hard to analyse gene expression data from DN...
Xue-Qiang Zeng, Guo-Zheng Li, Jack Y. Yang, Mary Q...
JMLR
2006
79views more  JMLR 2006»
13 years 9 months ago
Estimation of Gradients and Coordinate Covariation in Classification
We introduce an algorithm that simultaneously estimates a classification function as well as its gradient in the supervised learning framework. The motivation for the algorithm is...
Sayan Mukherjee, Qiang Wu
EDBT
2004
ACM
230views Database» more  EDBT 2004»
14 years 10 months ago
Flexible Integration of Molecular-Biological Annotation Data: The GenMapper Approach
Molecular-biological annotation data is continuously being collected, curated and made accessible in numerous public data sources. Integration of this data is a major challenge in ...
Hong Hai Do, Erhard Rahm
JBI
2004
171views Bioinformatics» more  JBI 2004»
13 years 11 months ago
Consensus Clustering and Functional Interpretation of Gene Expression Data
Microarray analysis using clustering algorithms can suffer from lack of inter-method consistency in assigning related gene-expression profiles to clusters. Obtaining a consensus s...
Paul Kellam, Stephen Swift, Allan Tucker, Veronica...
CSB
2005
IEEE
139views Bioinformatics» more  CSB 2005»
14 years 3 months ago
Predicting gene function by combining expression and interaction data
In this study we combined the spurious protein interaction data from the Database of Interacting Proteins with the recently published gene expression data of S. cerevisiae grown w...
Rogier J. P. van Berlo, Lodewyk F. A. Wessels, S. ...