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» Gene functional classification from heterogeneous data
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BMCBI
2008
96views more  BMCBI 2008»
13 years 10 months ago
Use of normalization methods for analysis of microarrays containing a high degree of gene effects
Background: High-throughput microarrays are widely used to study gene expression across tissues and developmental stages. Analysis of gene expression data is challenging in these ...
Terri T. Ni, William J. Lemon, Yu Shyr, Tao P. Zho...
SDM
2012
SIAM
252views Data Mining» more  SDM 2012»
12 years 11 days ago
Learning from Heterogeneous Sources via Gradient Boosting Consensus
Multiple data sources containing different types of features may be available for a given task. For instance, users’ profiles can be used to build recommendation systems. In a...
Xiaoxiao Shi, Jean-François Paiement, David...
FGCN
2008
IEEE
155views Communications» more  FGCN 2008»
13 years 11 months ago
Modeling the Marginal Distribution of Gene Expression with Mixture Models
We report the results of fitting mixture models to the distribution of expression values for individual genes over a broad range of normal tissues, which we call the marginal expr...
Edward Wijaya, Hajime Harada, Paul Horton
BIBM
2009
IEEE
155views Bioinformatics» more  BIBM 2009»
14 years 4 months ago
Towards Reliable Isoform Quantification Using RNA-Seq Data
Background: In eukaryotes, alternative splicing often generates multiple splice variants from a single gene. Here weexplore the use of RNA sequencing (RNA-Seq) datasets to address...
Brian E. Howard, Steffen Heber
BMCBI
2008
148views more  BMCBI 2008»
13 years 10 months ago
Discovering biclusters in gene expression data based on high-dimensional linear geometries
Background: In DNA microarray experiments, discovering groups of genes that share similar transcriptional characteristics is instrumental in functional annotation, tissue classifi...
Xiangchao Gan, Alan Wee-Chung Liew, Hong Yan