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» Gene functional similarity search tool (GFSST)
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BMCBI
2008
130views more  BMCBI 2008»
13 years 8 months ago
A database of phylogenetically atypical genes in archaeal and bacterial genomes, identified using the DarkHorse algorithm
Background: The process of horizontal gene transfer (HGT) is believed to be widespread in Bacteria and Archaea, but little comparative data is available addressing its occurrence ...
Sheila Podell, Terry Gaasterland, Eric E. Allen
BMCBI
2007
124views more  BMCBI 2007»
13 years 8 months ago
Protein structural similarity search by Ramachandran codes
Background: Protein structural data has increased exponentially, such that fast and accurate tools are necessary to access structure similarity search. To improve the search speed...
Wei-Cheng Lo, Po-Jung Huang, Chih-Hung Chang, Ping...
BMCBI
2006
144views more  BMCBI 2006»
13 years 8 months ago
ProFAT: a web-based tool for the functional annotation of protein sequences
Background: The functional annotation of proteins relies on published information concerning their close and remote homologues in sequence databases. Evidence for remote sequence ...
Charles Richard Bradshaw, Vineeth Surendranath, Bi...
BMCBI
2008
126views more  BMCBI 2008»
13 years 8 months ago
GeneChaser: Identifying all biological and clinical conditions in which genes of interest are differentially expressed
Background: The amount of gene expression data in the public repositories, such as NCBI Gene Expression Omnibus (GEO) has grown exponentially, and provides a gold mine for bioinfo...
Rong Chen, Rohan Mallelwar, Ajit Thosar, Shivkumar...
BMCBI
2004
150views more  BMCBI 2004»
13 years 8 months ago
SS-Wrapper: a package of wrapper applications for similarity searches on Linux clusters
Background: Large-scale sequence comparison is a powerful tool for biological inference in modern molecular biology. Comparing new sequences to those in annotated databases is a u...
Chunlin Wang, Elliot J. Lefkowitz