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» Gene functional similarity search tool (GFSST)
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BMCBI
2010
135views more  BMCBI 2010»
13 years 8 months ago
HDAPD: a web tool for searching the disease-associated protein structures
Background: The protein structures of the disease-associated proteins are important for proceeding with the structure-based drug design to against a particular disease. Up until n...
Yi-Ruen Lin, Hsin-Yuan Wei, Tsung-Lin Tsai, Thy-Ho...
GECCO
2007
Springer
131views Optimization» more  GECCO 2007»
14 years 2 months ago
Using feedback to regulate gene expression in a developmental control architecture
We present what we believe is the first attempt to physically reconstruct the exploratory mechanism of genetic regulatory networks. Feedback plays a crucial role during developme...
Kester Clegg, Susan Stepney, Tim Clarke
NAR
2011
227views Computer Vision» more  NAR 2011»
12 years 11 months ago
CADgene: a comprehensive database for coronary artery disease genes
Coronary artery disease (CAD) is a complex, multifactorial disease and a leading cause of mortality world wide. Over the past decades, great efforts have been made to elucidate th...
Hui Liu, Wei Liu, Yifang Liao, Long Cheng, Qian Li...
BMCBI
2006
107views more  BMCBI 2006»
13 years 8 months ago
Simplifying gene trees for easier comprehension
Background: In the genomic age, gene trees may contain large amounts of data making them hard to read and understand. Therefore, an automated simplification is important. Results:...
Paul-Ludwig Lott, Marvin Mundry, Christoph Sassenb...
BMCBI
2011
13 years 3 months ago
The PathOlogist: An Automated Tool for Pathway-Centric Analysis
Background: The PathOlogist is a new tool designed to transform large sets of gene expression data into quantitative descriptors of pathway-level behavior. The tool aims to provid...
Sharon I. Greenblum, Sol Efroni, Carl F. Schaefer,...