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» Gene set analysis for longitudinal gene expression data
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BMCBI
2010
113views more  BMCBI 2010»
13 years 7 months ago
Improving performance of mammalian microRNA target prediction
Background: MicroRNAs (miRNAs) are single-stranded non-coding RNAs known to regulate a wide range of cellular processes by silencing the gene expression at the protein and/or mRNA...
Hui Liu, Dong Yue, Yidong Chen, Shou-Jiang Gao, Yu...
BMCBI
2005
117views more  BMCBI 2005»
13 years 7 months ago
HmtDB, a Human Mitochondrial Genomic Resource Based on Variability Studies Supporting Population Genetics and Biomedical Researc
Background: Population genetics studies based on the analysis of mtDNA and mitochondrial disease studies have produced a huge quantity of sequence data and related information. Th...
Marcella Attimonelli, Matteo Accetturo, Monica San...
BMCBI
2004
114views more  BMCBI 2004»
13 years 7 months ago
Profiled support vector machines for antisense oligonucleotide efficacy prediction
Background: This paper presents the use of Support Vector Machines (SVMs) for prediction and analysis of antisense oligonucleotide (AO) efficacy. The collected database comprises ...
Gustavo Camps-Valls, Alistair M. Chalk, Antonio J....
GECCO
2010
Springer
191views Optimization» more  GECCO 2010»
14 years 7 days ago
Initialization parameter sweep in ATHENA: optimizing neural networks for detecting gene-gene interactions in the presence of sma
Recent advances in genotyping technology have led to the generation of an enormous quantity of genetic data. Traditional methods of statistical analysis have proved insufficient i...
Emily Rose Holzinger, Carrie C. Buchanan, Scott M....
BMCBI
2005
155views more  BMCBI 2005»
13 years 7 months ago
Mining protein function from text using term-based support vector machines
Background: Text mining has spurred huge interest in the domain of biology. The goal of the BioCreAtIvE exercise was to evaluate the performance of current text mining systems. We...
Simon B. Rice, Goran Nenadic, Benjamin J. Stapley