Achieving high classification accuracy is a major challenge in the diagnosis of cancer types based on gene expression profiles. These profiles are notoriously noisy in that a larg...
The Gene Ontology (GO) is an important knowledge resource for biologists and bioinformaticians. This paper explores the integration of similarity information derived from GO into ...
Haiying Wang, Francisco Azuaje, Olivier Bodenreide...
Background: Microarray pre-processing usually consists of normalization and summarization. Normalization aims to remove non-biological variations across different arrays. The norm...
Background: A typical step in the analysis of gene expression data is the determination of clusters of genes that exhibit similar expression patterns. Researchers are confronted w...
Evert-Jan Blom, Sacha A. F. T. van Hijum, Klaas J....
It is important in bioinformatics research and applications to select or discover informative genes of a tumor from microarray data. However, most of the existing methods are based...