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» Gene set analysis using principal components
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RECOMB
2001
Springer
14 years 11 months ago
Class discovery in gene expression data
Recent studies (Alizadeh et al, [1]; Bittner et al,[5]; Golub et al, [11]) demonstrate the discovery of putative disease subtypes from gene expression data. The underlying computa...
Amir Ben-Dor, Nir Friedman, Zohar Yakhini
SOQUA
2004
14 years 5 days ago
Measuring Component Performance Using A Systematic Approach and Environment
: As more third-party software components are available in the commercial market, more people begin to use the component-based software engineering approach to developing component...
Jerry Gao, Chandra S. Ravi, Raquel Espinoza
BMCBI
2006
200views more  BMCBI 2006»
13 years 11 months ago
Comparison and evaluation of methods for generating differentially expressed gene lists from microarray data
Background: Numerous feature selection methods have been applied to the identification of differentially expressed genes in microarray data. These include simple fold change, clas...
Ian B. Jeffery, Desmond G. Higgins, Aedín C...
BMCBI
2004
180views more  BMCBI 2004»
13 years 10 months ago
Noise filtering and nonparametric analysis of microarray data underscores discriminating markers of oral, prostate, lung, ovaria
Background: A major goal of cancer research is to identify discrete biomarkers that specifically characterize a given malignancy. These markers are useful in diagnosis, may identi...
Virginie M. Aris, Michael J. Cody, Jeff Cheng, Jam...
BMCBI
2010
131views more  BMCBI 2010»
13 years 11 months ago
Prediction of epigenetically regulated genes in breast cancer cell lines
Background: Methylation of CpG islands within the DNA promoter regions is one mechanism that leads to aberrant gene expression in cancer. In particular, the abnormal methylation o...
Leandro A. Loss, Anguraj Sadanandam, Steffen Durin...