—The most pervasive compute operation carried out in almost all bioinformatics applications is pairwise sequence homology detection (or sequence alignment). Due to exponentially ...
Background: Searching for approximate patterns in large promoter sequences frequently produces an exceedingly high numbers of results. Our aim was to exploit biological knowledge ...
Stefania Bortoluzzi, Alessandro Coppe, Andrea Biso...
Bioinformatics aims at applying computer science methods to the wealth of data collected in a variety of experiments in life sciences (e.g. cell and molecular biology, biochemistry...
Much of biology works by applying prior knowledge (`what is known') to an unknown entity, rather than the application of a set of axioms that will elicit knowledge. In additi...
Large scale bioinformatics experiments are usually composed by a set of data flows generated by a chain of activities (programs or services) that may be modeled as scientific work...