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BMCBI
2008
83views more  BMCBI 2008»
15 years 2 months ago
Integrative bioinformatics analysis of transcriptional regulatory programs in breast cancer cells
Background: Microarray technology has unveiled transcriptomic differences among tumors of various phenotypes, and, especially, brought great progress in molecular understanding of...
Atsushi Niida, Andrew D. Smith, Seiya Imoto, Shuic...
BMCBI
2008
96views more  BMCBI 2008»
15 years 2 months ago
The value of position-specific scoring matrices for assessment of protein allegenicity
Background: Bioinformatics tools are commonly used for assessing potential protein allergenicity. While these methods have achieved good accuracies for highly conserved sequences,...
Shen Jean Lim, Joo Chuan Tong, Fook Tim Chew, Mart...
BIBE
2008
IEEE
111views Bioinformatics» more  BIBE 2008»
15 years 4 months ago
Structure learning for biomolecular pathways containing cycles
Bayesian network structure learning is a useful tool for elucidation of regulatory structures of biomolecular pathways. The approach however is limited by its acyclicity constraint...
S. Itani, Karen Sachs, Garry P. Nolan, M. A. Dahle...
BMCBI
2010
214views more  BMCBI 2010»
15 years 2 months ago
AutoSOME: a clustering method for identifying gene expression modules without prior knowledge of cluster number
Background: Clustering the information content of large high-dimensional gene expression datasets has widespread application in "omics" biology. Unfortunately, the under...
Aaron M. Newman, James B. Cooper
ISCC
2002
IEEE
147views Communications» more  ISCC 2002»
15 years 7 months ago
A new method for finding generalized frequent itemsets in generalized association rule mining
Generalized association rule mining is an extension of traditional association rule mining to discover more informative rules, given a taxonomy. In this paper, we describe a forma...
Kritsada Sriphaew, Thanaruk Theeramunkong