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BMCBI
2010
96views more  BMCBI 2010»
13 years 10 months ago
QTLminer: identifying genes regulating quantitative traits
Background: Quantitative trait locus (QTL) mapping identifies genomic regions that likely contain genes regulating a quantitative trait. However, QTL regions may encompass tens to...
Rudi Alberts, Klaus Schughart
BMCBI
2008
113views more  BMCBI 2008»
13 years 10 months ago
Investigating selection on viruses: a statistical alignment approach
Background: Two problems complicate the study of selection in viral genomes: Firstly, the presence of genes in overlapping reading frames implies that selection in one reading fra...
Saskia de Groot, Thomas Mailund, Gerton Lunter, Jo...
BMCBI
2010
148views more  BMCBI 2010»
13 years 10 months ago
Structuring heterogeneous biological information using fuzzy clustering of k-partite graphs
Background: Extensive and automated data integration in bioinformatics facilitates the construction of large, complex biological networks. However, the challenge lies in the inter...
Mara L. Hartsperger, Florian Blöchl, Volker S...
BMCBI
2010
112views more  BMCBI 2010»
13 years 10 months ago
The MetabolomeExpress Project: enabling web-based processing, analysis and transparent dissemination of GC/MS metabolomics datas
Background: Standardization of analytical approaches and reporting methods via community-wide collaboration can work synergistically with web-tool development to result in rapid c...
Adam J. Carroll, Murray R. Badger, A. Harvey Milla...
BMCBI
2008
132views more  BMCBI 2008»
13 years 10 months ago
Exon level integration of proteomics and microarray data
Background: Previous studies comparing quantitative proteomics and microarray data have generally found poor correspondence between the two. We hypothesised that this might in par...
Danny A. Bitton, Michal J. Okoniewski, Yvonne Conn...
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