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BMCBI
2006
113views more  BMCBI 2006»
13 years 10 months ago
GibbsST: a Gibbs sampling method for motif discovery with enhanced resistance to local optima
Background: Computational discovery of transcription factor binding sites (TFBS) is a challenging but important problem of bioinformatics. In this study, improvement of a Gibbs sa...
Kazuhito Shida
BMCBI
2005
85views more  BMCBI 2005»
13 years 10 months ago
Processing methods for differential analysis of LC/MS profile data
Background: Liquid chromatography coupled to mass spectrometry (LC/MS) has been widely used in proteomics and metabolomics research. In this context, the technology has been incre...
Mikko Katajamaa, Matej Oresic
BMCBI
2011
13 years 5 months ago
Screening synteny blocks in pairwise genome comparisons through integer programming
Background: It is difficult to accurately interpret chromosomal correspondences such as true orthology and paralogy due to significant divergence of genomes from a common ancestor...
Haibao Tang, Eric Lyons, Brent S. Pedersen, James ...
BMCBI
2011
13 years 2 months ago
GPCR-SSFE: A comprehensive database of G-protein-coupled receptor template predictions and homology models
Background: G protein-coupled receptors (GPCRs) transduce a wide variety of extracellular signals to within the cell and therefore have a key role in regulating cell activity and ...
Catherine L. Worth, Annika Kreuchwig, Gunnar Klein...
ISPD
2012
ACM
289views Hardware» more  ISPD 2012»
12 years 6 months ago
Keep it straight: teaching placement how to better handle designs with datapaths
As technology scales and frequency increases, a new design style is emerging, referred to as hybrid designs, which contain a mixture of random logic and datapath standard cell com...
Samuel I. Ward, Myung-Chul Kim, Natarajan Viswanat...