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BMCBI
2010
104views more  BMCBI 2010»
13 years 7 months ago
Response network analysis of differential gene expression in human epithelial lung cells during avian influenza infections
Background: The recent emergence of the H5N1 influenza virus from avian reservoirs has raised concern about future influenza strains of high virulence emerging that could easily i...
Ken Tatebe, Ahmet Zeytun, Ruy M. Ribeiro, Robert H...
BMCBI
2008
153views more  BMCBI 2008»
13 years 7 months ago
AWclust: point-and-click software for non-parametric population structure analysis
Background: Population structure analysis is important to genetic association studies and evolutionary investigations. Parametric approaches, e.g. STRUCTURE and L-POP, usually ass...
Xiaoyi Gao, Joshua D. Starmer
BMCBI
2010
118views more  BMCBI 2010»
13 years 7 months ago
Computing H/D-Exchange rates of single residues from data of proteolytic fragments
Background: Protein conformation and protein/protein interaction can be elucidated by solution-phase Hydrogen/ Deuterium exchange (sHDX) coupled to high-resolution mass analysis o...
Ernst Althaus, Stefan Canzar, Carsten Ehrler, Mark...
BMCBI
2010
189views more  BMCBI 2010»
13 years 7 months ago
Efficient parallel and out of core algorithms for constructing large bi-directed de Bruijn graphs
Background: Assembling genomic sequences from a set of overlapping reads is one of the most fundamental problems in computational biology. Algorithms addressing the assembly probl...
Vamsi Kundeti, Sanguthevar Rajasekaran, Hieu Dinh,...
BMCBI
2008
130views more  BMCBI 2008»
13 years 7 months ago
A novel series of compositionally biased substitution matrices for comparing Plasmodium proteins
Background: The most common substitution matrices currently used (BLOSUM and PAM) are based on protein sequences with average amino acid distributions, thus they do not represent ...
Kevin Brick, Elisabetta Pizzi
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