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BMCBI
2010
103views more  BMCBI 2010»
13 years 7 months ago
Virtual Screening of potential drug-like inhibitors against Lysine/DAP pathway of Mycobacterium tuberculosis
Background: An explosive global spreading of multidrug resistant Mycobacterium tuberculosis (Mtb) is a catastrophe, which demands an urgent need to design or develop novel/potent ...
Aarti Garg, Rupinder Tewari, Gajendra P. S. Raghav...
BMCBI
2010
189views more  BMCBI 2010»
13 years 7 months ago
Efficient parallel and out of core algorithms for constructing large bi-directed de Bruijn graphs
Background: Assembling genomic sequences from a set of overlapping reads is one of the most fundamental problems in computational biology. Algorithms addressing the assembly probl...
Vamsi Kundeti, Sanguthevar Rajasekaran, Hieu Dinh,...
BMCBI
2008
176views more  BMCBI 2008»
13 years 7 months ago
H2r: Identification of evolutionary important residues by means of an entropy based analysis of multiple sequence alignments
Background: A multiple sequence alignment (MSA) generated for a protein can be used to characterise residues by means of a statistical analysis of single columns. In addition to t...
Rainer Merkl, Matthias Zwick
DCG
2008
118views more  DCG 2008»
13 years 7 months ago
General-Dimensional Constrained Delaunay and Constrained Regular Triangulations, I: Combinatorial Properties
Two-dimensional constrained Delaunay triangulations are geometric structures that are popular for interpolation and mesh generation because they respect the shapes of planar domai...
Jonathan Richard Shewchuk
BMCBI
2006
115views more  BMCBI 2006»
13 years 7 months ago
MitoRes: a resource of nuclear-encoded mitochondrial genes and their products in Metazoa
Background: Mitochondria are sub-cellular organelles that have a central role in energy production and in other metabolic pathways of all eukaryotic respiring cells. In the last f...
Domenico Catalano, Flavio Licciulli, Antonio Turi,...