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    JMLR
    2010
    97views more  JMLR 2010»
    Evaluation of a Bayesian model-based approach in GA studies
    13 years 2 months ago
    Evaluation of a Bayesian model-based approach in GA studies
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    In a typical Genetic Association Study (GAS) several hundreds to millions of genomic variables are measured and tested for association with a given set of a phenotypic variables (...
    Gábor Hullám, Peter Antal, Csaba Sza...
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    BMCBI
    2006
    119views more  BMCBI 2006»
    Utilization of two sample t-test statistics from redundant probe sets to evaluate different probe set algorithms in GeneChip stu
    13 years 7 months ago
    Utilization of two sample t-test statistics from redundant probe sets to evaluate different probe set algorithms in GeneChip stu
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    Background: The choice of probe set algorithms for expression summary in a GeneChip study has a great impact on subsequent gene expression data analysis. Spiked-in cRNAs with know...
    Zihua Hu, Gail R. Willsky
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    BMCBI
    2011
    252views Artificial Intelligence» more  BMCBI 2011»
    A hierarchical Bayesian network approach for linkage disequilibrium modeling and data-dimensionality reduction prior to genome-w
    12 years 11 months ago
    A hierarchical Bayesian network approach for linkage disequilibrium modeling and data-dimensionality reduction prior to genome-w
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    Background: Discovering the genetic basis of common genetic diseases in the human genome represents a public health issue. However, the dimensionality of the genetic data (up to 1...
    Raphael Mourad, Christine Sinoquet, Philippe Leray
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    JMLR
    2010
    162views more  JMLR 2010»
    A Surrogate Modeling and Adaptive Sampling Toolbox for Computer Based Design
    13 years 2 months ago
    A Surrogate Modeling and Adaptive Sampling Toolbox for Computer Based Design
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    An exceedingly large number of scientific and engineering fields are confronted with the need for computer simulations to study complex, real world phenomena or solve challenging ...
    Dirk Gorissen, Ivo Couckuyt, Piet Demeester, Tom D...
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    BMCBI
    2010
    106views more  BMCBI 2010»
    A novel approach for haplotype-based association analysis using family data
    13 years 7 months ago
    A novel approach for haplotype-based association analysis using family data
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    Background: Haplotype-based approaches have been extensively studied for case-control association mapping in recent years. It has been shown that haplotype methods can provide mor...
    Yixuan Chen, Xin Li, Jing Li
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