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» Genes, Themes, and Microarrays: Using Information Retrieval ...
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BMCBI
2006
119views more  BMCBI 2006»
13 years 7 months ago
LS-NMF: A modified non-negative matrix factorization algorithm utilizing uncertainty estimates
Background: Non-negative matrix factorisation (NMF), a machine learning algorithm, has been applied to the analysis of microarray data. A key feature of NMF is the ability to iden...
Guoli Wang, Andrew V. Kossenkov, Michael F. Ochs
BMCBI
2010
96views more  BMCBI 2010»
13 years 7 months ago
QTLminer: identifying genes regulating quantitative traits
Background: Quantitative trait locus (QTL) mapping identifies genomic regions that likely contain genes regulating a quantitative trait. However, QTL regions may encompass tens to...
Rudi Alberts, Klaus Schughart
BICOB
2009
Springer
13 years 5 months ago
A Biclustering Method to Discover Co-regulated Genes Using Diverse Gene Expression Datasets
We propose a two-step biclustering approach to mine co-regulation patterns of a given reference gene to discover other genes that function in a common biological process. Currently...
Doruk Bozdag, Jeffrey D. Parvin, Ümit V. &Cce...
BMCBI
2008
137views more  BMCBI 2008»
13 years 7 months ago
VennMaster: Area-proportional Euler diagrams for functional GO analysis of microarrays
Background: Microarray experiments generate vast amounts of data. The functional context of differentially expressed genes can be assessed by querying the Gene Ontology (GO) datab...
Hans A. Kestler, André Müller, Johann ...
BMCBI
2004
158views more  BMCBI 2004»
13 years 7 months ago
A novel Mixture Model Method for identification of differentially expressed genes from DNA microarray data
Background: The main goal in analyzing microarray data is to determine the genes that are differentially expressed across two types of tissue samples or samples obtained under two...
Kayvan Najarian, Maryam Zaheri, Ali Ajdari Rad, Si...