Abstract. Conserved regions, or motifs, present among RNA secondary structures serve as a useful indicator for predicting the functionality of the RNA molecules. Automated detectio...
Background: Bisulfite sequencing using next generation sequencers yields genome-wide measurements of DNA methylation at single nucleotide resolution. Traditional aligners are not ...
FLAN (short for FLu ANnotation), the NCBI web server for genome annotation of influenza virus (http://www.ncbi.nlm.nih.gov/genomes/FLU/ Database/annotation.cgi) is a tool for user...
Yiming Bao, Pavel Bolotov, Dmitry Dernovoy, Boris ...
Growing sequencing and assembly efforts have been met by the advances in high throughput machines. However, the presence of massive amounts of repeats and transposons complicates ...
Nirmalya Bandyopadhyay, A. Mark Settles, Tamer Kah...
Hidden Markov models (HMMs) have been successfully applied to a variety of problems in molecular biology, ranging from alignment problems to gene nding and annotation. Alignment p...