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» Genome Alignments Using MPI-LAGAN
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ISMB
2000
13 years 8 months ago
Mining for Putative Regulatory Elements in the Yeast Genome Using Gene Expression Data
We have developed a set of methods and tools for automatic discovery of putative regulatory signals in genome sequences. The analysis pipeline consists of gene expression data clu...
Jaak Vilo, Alvis Brazma, Inge Jonassen, Alan J. Ro...
BMCBI
2006
86views more  BMCBI 2006»
13 years 7 months ago
MCALIGN2: Faster, accurate global pairwise alignment of non-coding DNA sequences based on explicit models of indel evolution
Background: Non-coding DNA sequences comprise a very large proportion of the total genomic content of mammals, most other vertebrates, many invertebrates, and most plants. Unravel...
Jun Wang, Peter D. Keightley, Toby Johnson
BIBM
2009
IEEE
118views Bioinformatics» more  BIBM 2009»
13 years 11 months ago
Inexact Local Alignment Search over Suffix Arrays
We describe an algorithm for finding approximate seeds for DNA homology searches. In contrast to previous algorithms that use exact or spaced seeds, our approximate seeds may conta...
Mohammadreza Ghodsi, Mihai Pop
BMCBI
2010
148views more  BMCBI 2010»
13 years 7 months ago
Calling SNPs without a reference sequence
Background: The most common application for the next-generation sequencing technologies is resequencing, where short reads from the genome of an individual are aligned to a refere...
Aakrosh Ratan, Yu Zhang, Vanessa M. Hayes, Stephan...
CSB
2003
IEEE
14 years 24 days ago
A New Approach for Gene Annotation Using Unambiguous Sequence Joining
The problem addressed by this paper is accurate and automatic gene annotation following precise identification/annotation of exon and intron boundaries of biologically verified ...
Alexandre Tchourbanov, Daniel Quest, Hesham H. Ali...