We present a solution for the following problem. Given two sequences X = x1x2 · · · xn and Y = y1y2 · · · ym, n ≤ m, find the best scoring alignment of X = Xk [i] vs Y ove...
Algorithm development for comparing and aligning biological sequences has, until recently, been based on the SI model of mutational events which assumes that modi cation of sequen...
Background: Pathogen diagnostic assays based on polymerase chain reaction (PCR) technology provide high sensitivity and specificity. However, the design of these diagnostic assays...
Ravi Vijaya Satya, Kamal Kumar, Nela Zavaljevski, ...
Background: For the purposes of finding and aligning noncoding RNA gene- and cis-regulatory elements in multiple-genome datasets, it is useful to be able to derive multi-sequence ...
Background: Non-coding RNAs (ncRNAs) have a multitude of roles in the cell, many of which remain to be discovered. However, it is difficult to detect novel ncRNAs in biochemical s...
Andrew V. Uzilov, Joshua M. Keegan, David H. Mathe...