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» Genome Alignments Using MPI-LAGAN
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CPM
2001
Springer
72views Combinatorics» more  CPM 2001»
14 years 1 months ago
Tandem Cyclic Alignment
We present a solution for the following problem. Given two sequences X = x1x2 · · · xn and Y = y1y2 · · · ym, n ≤ m, find the best scoring alignment of X = Xk [i] vs Y ove...
Gary Benson
RECOMB
1997
Springer
14 years 23 days ago
Sequence alignment with tandem duplication
Algorithm development for comparing and aligning biological sequences has, until recently, been based on the SI model of mutational events which assumes that modi cation of sequen...
Gary Benson
BMCBI
2010
94views more  BMCBI 2010»
13 years 8 months ago
A high-throughput pipeline for the design of real-time PCR signatures
Background: Pathogen diagnostic assays based on polymerase chain reaction (PCR) technology provide high sensitivity and specificity. However, the design of these diagnostic assays...
Ravi Vijaya Satya, Kamal Kumar, Nela Zavaljevski, ...
BMCBI
2004
126views more  BMCBI 2004»
13 years 8 months ago
A probabilistic model for the evolution of RNA structure
Background: For the purposes of finding and aligning noncoding RNA gene- and cis-regulatory elements in multiple-genome datasets, it is useful to be able to derive multi-sequence ...
Ian Holmes
BMCBI
2006
158views more  BMCBI 2006»
13 years 8 months ago
Detection of non-coding RNAs on the basis of predicted secondary structure formation free energy change
Background: Non-coding RNAs (ncRNAs) have a multitude of roles in the cell, many of which remain to be discovered. However, it is difficult to detect novel ncRNAs in biochemical s...
Andrew V. Uzilov, Joshua M. Keegan, David H. Mathe...