The assignment of orthologous genes between a pair of genomes is a fundamental and challenging problem in comparative genomics, since many computational methods for solving variou...
Zheng Fu, Xin Chen, Vladimir Vacic, Peng Nan, Yang...
The Distributed Annotation System (DAS) is a protocol for sharing of biological data which allows for dynamical data integration. It has become widely used in both the genome and p...
Andreas Prlic, Ewan Birney, Tony Cox, Thomas A. Do...
Background: The Ensembl project produces updates to its comparative genomics resources with each of its several releases per year. During each release cycle approximately two week...
Jessica Severin, Kathryn Beal, Albert J. Vilella, ...
Background: Understanding transcriptional regulation of gene expression is one of the greatest challenges of modern molecular biology. A central role in this mechanism is played b...
Background: Alignment and comparison of related genome sequences is a powerful method to identify regions likely to contain functional elements. Such analyses are data intensive, ...
Gregory M. Cooper, Senthil A. G. Singaravelu, Aren...