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» Genome Sequence Assembly: Algorithms and Issues
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BICOB
2009
Springer
14 years 3 months ago
Assembly of Large Genomes from Paired Short Reads
The de novo assembly of genomes from high-throughput short reads is an active area of research. Several promising methods have been recently developed, with applicability mainly re...
Benjamin G. Jackson, Patrick S. Schnable, Srinivas...
BIBM
2010
IEEE
286views Bioinformatics» more  BIBM 2010»
13 years 6 months ago
Evaluation of short read metagenomic assembly
Advances in sequencing technologies have equipped researchers with the ability to sequence the collective genome of entire microbial communities commonly referred to as metagenomi...
Anveshi Charuvaka, Huzefa Rangwala
BMCBI
2008
116views more  BMCBI 2008»
13 years 8 months ago
Clustering exact matches of pairwise sequence alignments by weighted linear regression
Background: At intermediate stages of genome assembly projects, when a number of contigs have been generated and their validity needs to be verified, it is desirable to align thes...
Alvaro J. González, Li Liao
BIOCOMP
2007
13 years 10 months ago
xMAN: extreme MApping of oligoNucleotides
Background: The ability to rapidly map millions of oligonucleotide fragments to a reference genome is crucial to many high throughput genomic technologies. Results: We propose an ...
Wei Li, Jason S. Carroll, Myles Brown, X. Shirley ...
BMCBI
2010
148views more  BMCBI 2010»
13 years 8 months ago
Calling SNPs without a reference sequence
Background: The most common application for the next-generation sequencing technologies is resequencing, where short reads from the genome of an individual are aligned to a refere...
Aakrosh Ratan, Yu Zhang, Vanessa M. Hayes, Stephan...