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» Genome Sequence Assembly: Algorithms and Issues
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BMCBI
2010
100views more  BMCBI 2010»
13 years 8 months ago
Scaffold filling, contig fusion and comparative gene order inference
Background: There has been a trend in increasing the phylogenetic scope of genome sequencing without finishing the sequence of the genome. Increasing numbers of genomes are being ...
Adriana Muñoz, Chunfang Zheng, Qian Zhu, Vi...
BMCBI
2011
13 years 4 days ago
Combinatorial analysis and algorithms for quasispecies reconstruction using next-generation sequencing
Background: Next-generation sequencing (NGS) offers a unique opportunity for high-throughput genomics and has potential to replace Sanger sequencing in many fields, including de-n...
Mattia C. F. Prosperi, Luciano Prosperi, Alessandr...
BMCBI
2008
99views more  BMCBI 2008»
13 years 8 months ago
Multiple organism algorithm for finding ultraconserved elements
Background: Ultraconserved elements are nucleotide or protein sequences with 100% identity (no mismatches, insertions, or deletions) in the same organism or between two or more or...
Scott Christley, Neil F. Lobo, Gregory R. Madey
CEC
2008
IEEE
14 years 3 months ago
A self-adaptive cellular memetic algorithm for the DNA fragment assembly problem
Abstract— The DNA fragment assembly problem is to reconstruct a DNA chain from multiple fragments that have previously been sequenced in a laboratory. This is a critical step in ...
Bernabé Dorronsoro, Enrique Alba, Gabriel L...
WABI
2009
Springer
181views Bioinformatics» more  WABI 2009»
14 years 3 months ago
Decoding Synteny Blocks and Large-Scale Duplications in Mammalian and Plant Genomes
Abstract. The existing synteny block reconstruction algorithms use anchors (e.g., orthologous genes) shared over all genomes to construct the synteny blocks for multiple genomes. T...
Qian Peng, Max A. Alekseyev, Glenn Tesler, Pavel A...