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BMCBI
2004
150views more  BMCBI 2004»
13 years 8 months ago
Cross-species comparison significantly improves genome-wide prediction of cis-regulatory modules in Drosophila
Background: The discovery of cis-regulatory modules in metazoan genomes is crucial for understanding the connection between genes and organism diversity. It is important to quanti...
Saurabh Sinha, Mark D. Schroeder, Ulrich Unnerstal...
BMCBI
2006
103views more  BMCBI 2006»
13 years 8 months ago
Cis-motifs upstream of the transcription and translation initiation sites are effectively revealed by their positional disequili
Background: The discovery of cis-regulatory motifs still remains a challenging task even though the number of sequenced genomes is constantly growing. Computational analyses using...
Kenneth W. Berendzen, Kurt Stüber, Klaus Hart...
GECCO
2009
Springer
173views Optimization» more  GECCO 2009»
14 years 3 months ago
Creating regular expressions as mRNA motifs with GP to predict human exon splitting
Low correlation between mRNA concentrations measured at different locations for the same exon show many current Ensembl exon definitions are incomplete. Automatically created pa...
William B. Langdon, Joanna Rowsell, Andrew P. Harr...
BMCBI
2011
13 years 5 days ago
Proportion statistics to detect differentially expressed genes: a comparison with log-ratio statistics
Background: In genetic transcription research, gene expression is typically reported in a test sample relative to a reference sample. Laboratory assays that measure gene expressio...
Tracy L. Bergemann, Jason Wilson
IFIP
2004
Springer
14 years 1 months ago
Efficient Algorithms for Handling Molecular Weighted Sequences
Abstract In this paper we introduce the Weighted Suffix Tree, an efficient data structure for computing string regularities in weighted sequences of molecular data. Molecular Wei...
Costas S. Iliopoulos, Christos Makris, Yannis Pana...